RESUMEN
Se describen los casos de tres pacientes con trombocitopenia persistente luego de haber padecido dengue hemorrágico de evolución aguda, crónica, respondedora y resistente a los esteroides.
Estos casos sucedieron durante la epidemia de dengue de 2009 en Nayarit, México. Los tres pacientes tuvieron características similares a las de quienes sufren púrpura trombocitopénica idiopática.
La clínica y los resultados de laboratorio fueron diferentes entre ellos; igual sucedió en lo referente a la respuesta al tratamiento.
Se concluye que la infección por dengue debe considerarse causa de púrpura trombocitopénica idiopática y conceptualizarse como un síndrome trombocitopénico y no como una enfermedad independiente.
Palabras claves: púrpura trombocitopénica idiopática, dengue hemorrágico.
ABSTRACT
Idiopathic thrombocytopenic purpura (ITP) is diagnosed by exclusion, still appear illnesses associated with ITP, the latter were infected with hepatitis C virus and Helicobacter pylori. The objective is describe three patients with persistent thrombocytopenia after suffering with dengue hemorrhagic fiber with presentations clinical diversity including acute, chronic, responder and refractory to steroid. We describe three patients with persistent thrombocytopenia, had dengue hemorrhagic fiber on dengue epidemic in 2009 in Nayarit, Mexico. The three reported cases had similar characteristics to patients with ITP. With laboratory and clinical diversity among them, all were adults, two women and one man, one had complete remission with steroids, one only refers to the administration of steroids and the other is refractory to steroids. Dengue virus infection should be considered as a cause of PTI. This should be conceptualized as a syndrome thrombocytopenic and not as a separate disease. Might not be appropriate to the classification of primary and secondary ITP, simply place it as a cause thrombocytopenic syndrome to be identified.
Key words: ITP, Dengue Hemorrhagic Fever.